論文リスト
2024
Bakuchiol targets mitochondrial proteins, prohibitins and voltage-dependent anion channels: new insights into developing antiviral agents. Shoji, M.; Esumi, T.; Masuda, T.; Tanaka, N.; Okamoto, R.; Sato, H.; Watanabe, M.; Takahashi, E.; Kido, K.; Ohtsuki, S.; Kuzuhara, T. J. Biol. Chem. 2024, 300, 105632-105645.
Organic Synthesis and anti-Influenza A Virus Activity of Cyclobakuchiols A, B, C, and D. Shoji, M.; Esumi, T.; Tanaka, N.; Takeuchi, M.; Yamaji, S.; Watanabe, M.; Takahashi, E.; Kido, H.; Yamamoto, M.; Kuzuhara, T. PLoS ONE 2021, 16(3), e0248960.
Bakuchiol is a Phenolic Isoprenoid with Novel Enantiomer-Selective Anti-Influenza A Virus Activity Involving Nrf2 Activation. Shoji, M.; Arakaki, Y.; Esumi, T.; Kohnomi, S.; Yamamoto, C.; Suzuki, Y.; Takahashi, E.; Konishi, S.; Kido, H.; Kuzuhara, T. J. Biol. Chem. 2015, 290, 28001-28017.
Systematic Asymmetric Synthesis of All Diastereomers of (–)-Talaumidin and Their Neurotrophic Activity. Harada, K.; Kubo, M.; Horiuchi, H.; Ishii, A.; Esumi, T.; Hioki, H.; Fukuyama, Y. J. Org. Chem. 2015, 80, 7076-7088.
Total synthesis of riccardin C and (±)-cavicularin via Pd-catalyzed Ar-Ar cross couplings. Harada, K.; Makino, K.; Shima, N.; Okuyama, H.; Esumi, T.; Kubo, M.; Hioki, H.; Asakawa, Y.; Fukuyama, Y. Tetrahedron 2013, 69, 6959-6968.
A short synthesis of (+)-bakuchiol. Esumi, T.; Yamamoto, C.; Fukuyama, Y. Synlett 2013, 24, 1845-1847.
Construction of successive chiral center adjacent to chiral tetraalkylated quaternqanry center using an asymmetric aldol reaction. Esumi, T.; Yamamoto, C.; Tsugawa, Y.; Toyota, M.; Asakawa, Y.; Fukuyama, Y. Org. Lett. 2013, 15, 1898-1901.
Identification and purification of resorcinol, an antioxidant specific to Awa-ban (picked and anaerobically fermented) tea. Hiasa, M.; Kurokawa, M.; Ohta, K.; Esumi, T.; Akita, H.; Niki, K.; Yagi, Y.; Echigo, N.; Hatakeyama, D.; Kuzuhara, T. Food Research International 2013, 54, 72-80.
Total synthesis of (+)-brefeldin C utilizing aza-Claisen rearrangement. Inai, M.; Nishii, T.; Mukoujima, S.; Esumi, T.; Kaku, H.; Abe, H.; Horikawa, M.; Tsunoda, T. Synlett 2011, 10, 1459-1461.
First enantiocontrolled formal synthesis of (+)-neovibsanin B, A neurotrophic diterpenoid. Esumi, T.; Mori, T.; Zhao, M.; Toyota, M.; Fukuyama, Y. Org. Lett. 2010, 12, 888-891.
Total synthesis of (+)-fostriecin and (+)-phoslactomycin B. Shibahara, S.; Fujino, M.; Tashiro, Y.; Okamoto, N.; Esumi, T.; Takahashi, K.; Ishihara, J.; Hatakeyama, S. Synthesis 2009, 17, 2935-2953.
Efficient construction of a chiral all-carbon quaternary center by asymmetric 1,4-addition and its application to total synthesis of (+)-bakuchiol. Esumi, T.; Shimizu, H.; Kashiyama, A.; Sasaki, C.; Toyota, M.; Fukuyama, Y. Tetrahedron Lett. 2008, 49, 6846-6849.
Synthesis of (–)-talaumidin, a neurotrophic 2,5-biaryl-3,4-dimethyltetrahydrofuran lignan, and its stereoisomers. Fukuyama, Y.; Harada, H.; Esumi, T.; Hojyo, D.; Kujime, Y.; Kubo, M.; Hioki, H. Heterocycles, 2008, 76, 551-567.
Synthetic studies toward neovibsanins A and B: construction of of the neovibsanin core utilizing palladium(0)-catalyzed carbonylative cyclization with carbon monoxid. Esumi, T.; Zhao, M.; Kawakami, T.; Fukumoto, M.; Toyota, M.; Fukuyama, Y. Tetrahedron Lett. 2008, 49, 2692-2696.
First enantioselective synthesis of (+)-talaumidin, a neurotrophic diaryltetrahydrofuran-type lignan. Esumi, T.; Hojyo, D.; Zhai, H.; Fukuyama, Y. Tetrahedron Lett. 2006, 45, 3979-3983.
Efficient synthesis of isoplagiochin D, a macrocyclic bis(bibenzyls), by utilizing an intramolecular Suzuki-Miyaura reaction. Esumi, T.; Wada, M.; Mizushima, E.; Sato, N., Kodama, M., Asakawa, Y., Fukuyama, Y. Tetrahedron Lett. 2004, 45, 6941-6945.
Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan. Esumi, T.; Makado, G.; Zhai, H.; Shimizu, Y.; Mitsumoto, Y.; Fukuyama, Y. Bioorg. Med. Chem. Soc. 2004, 14, 2621-2625.
Versatile enantiocontrolled synthesis of (+)-fostriecin. Esumi, T.; Okamoto, N.; Hatakeyama, S. Chem. Commun. 2002, 3042-3043.