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| 2023年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
| Suppressive effects of docosahexaenoic acid intake on increased seizure susceptibility after growth due to febrile seizures. Shinji Kawano, Kouichi Itoh, Yasuhiro Ishihara. Biological and Pharmaceutical Bulletin in press |  |
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| Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation. Miki Tanaka, Tomoaki Okuda, Kouichi Itoh, Nami Ishihara, Ami Oguro, Yoshiaki Fujii-Kuriyama, Yu Nabetani, Megumi Yamamoto, Christoph F.A. Vogel, Yasuhiro Ishihara. Particle and Fibre Toxicology (2023) 20:6 https://doi.org/10.1186/s12989-023-00517-x | |
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| Microglial inflammatory reactions regulated by oxidative stress. Yasuhiro Ishihara, Kouichi Itoh Journal of Clinical Biochemistry and Nutrition (2023) 72:23-27 https://doi.org/10.3164/jcbn.22-71 | |
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| 2022年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
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A CCR5 antagonist, maraviroc, alleviates neural circuit dysfunction and behavioral disorders induced by prenatal valproate exposure. Yasuhiro Ishihara, Tatsuya Honda1, Nami Ishihara1, Kaede Namba1, Makiko Taketoshi, Yoko Tominaga, Mayumi Tsuji, Christoph F. A. Vogel, Takeshi Yamazaki, Kouichi Itoh and Takashi Tominaga. Journal of Neuroinflammation (2022) 19:195. https://doi.org/10.1186/s12974-022-02559-y |
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Levetiracetam Suppresses the Infiltration of Neutrophils and Monocytes and Downregulates Many Inflammatory Cytokines during Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice. Taira Matsuo, Rie Komori, Minami Nakatani, Shiori Ochi, Aya Yokota-Nakatsuma, Junichi Matsumoto, Fuyuko Takata, Shinya Dohgu, Yasuhiro Ishihara and Kouichi Itoh. Int. J. Mol. Sci. (2022) 23, 7671. https://doi.org/10.3390/ ijms23147671 |
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Regulation of Inflammation-Related Genes through Fosl1 Suppression in a Levetiracetam-Treated Pilocarpine-Induced Status Epilepticus Mouse Model. Rie Komori, Taira Matsuo, Aya Yokota-Nakatsuma , Ritsuka Hashimoto, Shizuka Kubo, Chihiro Kozawa Tomomi Kono Yasuhiro Ishihara and Kouichi Itoh. Int. J. Mol. Sci. (2022) 23, 7608. https://doi.org/ 10.3390/ijms23147608 |
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Involvement of polycyclic aromatic hydrocarbons and endotoxin in macrophage expression of interleukin-33 induced by exposure to particulate matter. Nami Ishihara, Tomoaki Okuda, Hiroyuki Hagino, Ami Oguro, Yuto Tani, Hiroshi Okochi, Chiharu Tokoro, Yoshiaki Fujii-Kuriyama, Kouichi Itoh, Christoph F.A. Vogel, Yasuhiro Ishihara. J. Toxicol. Sci., (2022) 47:201-210 |
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| 2021年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
| FosL1 Is a Novel Target of Levetiracetam for Suppressing the Microglial Inflammatory Reaction. Kouji Niidome, Ruri Taniguchi, Takeshi Yamazaki, Mayumi Tsuji, Kouichi Itoh and Yasuhiro Ishihara. Int. J. Mol. Sci. 2021, 22, 10962. https://doi.org/10.3390/ijms222010962 | |
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| Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice..Kenta Sakai, Fuyuko Takata, Gaku Yamanaka b, Miho Yasunaga a, Kana Hashiguchi, Kazuki Tominaga, Kouichi Itoh, Yasufumi Kataoka, Atsushi Yamauchi, Shinya Dohgu.. J. Pharmacol. Sci. 2021 145:155-165 | |
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| Maternal intake of docosahexaenoic acid decreased febrile seizuresensitivity by increasing estrogen synthesis in offspring. Shinji Kawano, Kouichi Itoh, Yasuhiro Ishihara. Epilepsy & Behavior 2021 121: 108038 | |
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| 2020年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
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Masahiro Ishii, Ayako Senju, Ami Oguro, Masayuki Shimono, Shunsuke Araki, Koichi Kusuhara, Kouichi Itoh, Mayumi Tsuji, Yasuhiro Ishihara. (2020) Measurement of the Estradiol Concentration in Cerebrospinal Fluid from Infants and Its Correlation with Serum Estradiol and Exosomal MicroRNA-126-5p. Biol. Pharm. Bull. 43:1966-1968 |
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| 2019年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
| Yasuhiro Ishihara, Kouichi Itoh, Ami Oguro, Yoichi Chiba, Masaki Ueno, Mayumi Tsuji, Christoph F. A. Vogel, Takeshi Yamazaki. Neuroprotective activation of astrocytes by methylmercury exposure in the inferior colliculus. Scientific Reports (2019) 9:13899 https://doi.org/10.1038/s41598-019-50377-9 |
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| Kouichi Itoh, Ruri Taniguchi, Taira Matsuo, Ami Oguro, Christoph F.A. Vogelc, Takeshi Yamazaki, Yasuhiro Ishihara. Suppressive effects of levetiracetam on neuroinflammation and phagocytic microglia: A comparative study of levetiracetam, valproate and carbamazepine. Neuroscience Letters 708 (2019) 134363 https://doi.org/10.1016/j.neulet.2019.134363 |
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| 2018年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
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M. Kotani, K. Itoh, et al Two non-cytotoxic type 2 ribosome-inactivating proteins (Sambucus Sieboldiana lectin and Sambucus Nigra lectin) lead neurosphere cells to caspase-independent apoptosis. Biomedical Research (2018) 29:1570-1577 |
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M. Tanaka, Y. Ishihara, S. Mizuno, A. Ishida, C. F. Vogel, M. Tsuji , T. Yamazak, K. Itoh. Progression of vasogenic edema induced by activated microglia under permanent middle cerebral artery occlusion. Biochem. Biophys. Res. Comm., 496:582-587, 2018. |
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| 2017年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | |
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Y. Ishihara, K. Itoh, M. Tanaka, M. Tsuji, T. Kawamoto, S. Kawato, C. F.A.Vogel, T. Yamazaki. Potentiation of 17β-estradiol synthesis in the brain and elongation of seizure latency through dietary supplementation with docosahexaenoic acid. Scientific Reports 2017, 7: 6268 DOI:10.1038/s41598-017-06630-0 |
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| 2016年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） | ||
| 1. | Kotani, M., Sato, Y., Ueno, A., Ito, T., Itoh, K., Imadae, M. A Novel Monoclonal Antibody against Neuroepithelial and Ependymal Cells and Characteristics of Its Positive Cells in Neurospheres, Cellular and Molecular Neurobiology 36:11-26, 2016. |
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| 2. | Kouichi Itoh, Yasuhiro Ishihara Rie Komori, Hiromi Nochi, Ruri Taniguchi, Yoichi Chiba, Masaki Ueno, Fuyuko Takata-Tsuji, Shinya Dohgu, Yasufumi Kataoka, Levetiracetam treatment influences blood-brain barrier failure associated with angiogenesis and inflammatory responses in the acute phase of epileptogenesis in post-status epilepticus mice Brain Res., 1652:1-13, 2016 |
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| 2015年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） |
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1.
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Yasuhiro Ishihara, Takuya Takemoto, Kouichi Itoh, Atsuhiko Ishida, Takeshi Yamazaki. Dual Role of Superoxide Dismutase 2 Induced in Activated Microglia: Oxidative Stress Tolerance and Convergence of Inflammatory Responses J. Biol. Chem. 290:22805-22817, 2015 |
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2.
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Itoh, K., Mizuno, S., Hama, S., Oshima, W., Kawamata, M., Hossain, A., Ishihara, Y., Tokuda, M. Beneficial effects of supplementation of the rare sugar “D-allulose” against hepatic steatosis and severe obesity in Lepob/Lepob mice. J. Food Sci 80:H1619-H1626, 2015 |
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3.
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Y. Ishihara, K. Itoh, A. Ishida, T., Yamazaki. Selective estrogen-receptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway. J. Steroid Biochem. Mol. Biol., 145:85-93, 2015. |
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4.
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K. Itoh, M. Inamine, W. Oshima, M. Kotani, Y. Chiba, M. Ueno, Y. Ishihara. Prevention of status epilepticus-induced brain edema and neuronal cell loss by repeated treatment with high-dose levetiracetam Brain Reserch 1608:225-234, 2015. |
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5.
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伊藤康一, 我が国における新規抗てんかん薬 香川県薬剤師会誌 156:54-57, 2015 |
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| 2014年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） |
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1.
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Kobayashi T., Komori R., Ishida K., Kino K., Tanuma S., Miyazawa H., Tal2 expression is induced by all-trans retinoic acid in P19 cells prior to acquisition of neural fate. Sci. Rep., 4, 4935, 2014. |
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| 2013年 | 著者(太字・アンダーライン：教員、太字：大学院・学部学生） |
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1.
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Danjo, S., Ishihara, Y., Watanabe, M., Nakamura, Y., Itoh, K., Pentylentetrazole-induced the Loss of Blood-brain Barrier Integrity is Involved in Neuronal Nitric Oxide Synthase-derived Excess Nitric Oxide Generation, Brain Research 1530:44-53, 2013 |
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3.
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Watanabe, M., Miyai, A., Danjo, S., Nakamura, Y., Itoh, K. The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains. Experimental Neurology 247:645?652, 2013 |
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4.
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Hirotada G Fujii, Hideo Sato-Akaba, Miho C Emoto, Kouichi Itoh, Yasuhiro Ishihara, Hiroshi Hirata, Noninvasive mapping of the redox status in septic mouse by in vivo electron paramagnetic resonance imaging, Magn. Reson. Img. 31:130-138, 2013 |
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