Chihiro Kurematsu, Masato Sawada, Masaki Ohmuraya, Motoki Tanaka, Kazuya Kuboyama, Takashi Ogino, Mami Matsumoto, Hisashi Oishi, Hiroyuki Inada, Yuri Ishido, Yukina Sakakibara, Huy Nguyen, Quynh Thai, Shinichi Kohsaka, Nobuhiko Ohno, Maki Yamada, Masato Asai, Masahiro Sokabe, Junichi Nabekura, Kenichi Asano, Matsato Tanaka, and Kazunobu Sawamoto.
Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine
J Exp Med (2022) 219 (4): e20202304.
Kuboyama K, Inoue T, Hashimotodani Y, Itoh T, Suzuki T, Tetsuzawa A, Ohtsuka Y, Kinoshita R., Takara R, Miyazawa T, Gusain P, Kano M, Yamada MK.
Traceable stimulus-dependent rapid molecular changes in dendritic spines in the brain
Scientific Reports volume 10, Article number: 15266 (2020)
DOI : 10.1038/s41598-020-72248-4
Kuboyama, K., Shirakawa, Y., Kawada, K., Fujii, N., Ojima, D., Kisimoto, Y., Yamamoto, T., and Yamada, M.K.
Visually cued fear conditioning test for memory impairment related to cortical function
Neuropsychopharmacology Reports, 40(4) 371-375 (2020)
doi/10.1002/npr2.12146
Kuboyama K, Inoue T, Hashimotodani Y, Itoh T, Suzuki T, Tetsuzawa A, Kinoshita R, Ohtsuka Y, Takara R, Miyazawa T, Gusain P, Kano M, Yamada MK.
Fluorescent Marker of a Plasticity-Related Change in Dendritic Spines.
Sneak Peek (Preprint)
doi: 10.2139/ssrn.3419080
Fujikawa A, Sugawara H, Tanga N, Ishii K, Kuboyama K, Uchiyama S, Suzuki R, Noda M. [at National Institute for Basic Biology (NIBB)]
A head-to-toe dimerization has physiological relevance for ligand-induced inactivation of protein tyrosine receptor type Z.
The Journal of Biological Chemistry 294: 14953-14965 (2019)
doi: 10.1074/jbc.RA119.007878
Tanga N, Kuboyama K, Kishimoto A, Kihara M, Kiyonari H, Watanabe T, Fujikawa A, Noda M. (at NIBB)
Behavioral and neurological analyses of adult mice carrying null and distinct loss-of-receptor function mutations in protein tyrosine phosphatase receptor type Z (PTPRZ).
PLOS ONE 14: e0217880 (2019)
doi: 10.1371/journal.pone.0217880
Tanga N, Kuboyama K, Kishimoto A, Kiyonari H, Shiraishi A, Suzuki R, Watanabe T, Fujikawa A, Noda M. (at NIBB)
The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice.
GLIA 67: 967-984 (2019)
doi: 10.1002/glia.23583
Suzuki R, Fujikawa A, Komatsu Y, Kuboyama K, Tanga N, Noda M. (at NIBB)
Enhanced extinction of aversive memories in mice lacking SPARC-related protein-containing immunoglobulin domains 1 (SPIG1/FSTL4).
Neurobiology of Learning and Memory 152: 61-70 (2018)
doi: 10.1016/j.nlm.2018.05.010
Kuboyama K, Tanga N, Suzuki R, Fujikawa A, Noda M. (at NIBB)
Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation.
PLOS ONE 12: e0189164 (2017)
doi: 10.1371/journal.pone.0189164
Fujikawa A, Sugawara H, Tanaka T, Matsumoto M, Kuboyama K, Suzuki R, Tanga N, Ogata A, Masumura M, Noda M. (at NIBB)
Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells.
Scientific Reports 7: 5609 (2017)
doi: 10.1038/s41598-017-05931-8
Fujikawa A, Chow JP, Matsumoto M, Suzuki R, Kuboyama K, Yamamoto N, Noda M. (at NIBB)
Identification of novel splicing variants of protein tyrosine phosphatase receptor type Z.
The Journal of Biochemistry 1621: 381-390 (2017)
doi: 10.1093/jb/mvx042
Yamada MK.
A link between vascular damage and cognitive deficits after whole-brain radiation therapy for cancer: A clue to other types of dementia?
Drug Discoveries & Therapeutics 10: 79-81 (2016)
doi: 10.5582/ddt.2016.01004
Yamada MK.
Angiogenesis in refractory depression: A possible phenotypic target to avoid the blood brain barrier.
Drug Discoveries & Therapeutics 10: 74-78 (2016)
doi: 10.5582/ddt.2016.01003
Ikeda T, Makino Y, Yamada MK.
17α-Estradiol is generated locally in the male rat brain and can regulate GAD65 expression and anxiety.
Neuropharmacology 90: 9-14 (2015)
doi: 10.1016/j.neuropharm.2014.10.019
Hamamoto H, Urai M, Ishii K, Yasukawa J, Paudel A, Murai M, Kaji T, Kuranaga T, Hamase K, Katsu T, Su J, Adachi T, Uchida R, Tomoda H, Yamada MK, Souma M, Kurihara H, Inoue M, Sekimizu K.
Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane.
Nature Chemical Biology 11: 127-133 (2015)
doi: 10.1038/nchembio.1710
Peng YR, Zeng SY, Song HL, Li MY, Yamada MK, Yu X.
Postsynaptic spiking homeostatically induces cell-autonomous regulation of inhibitory inputs via retrograde signaling.
The Journal of Neuroscience 30: 16220-16231 (2010)
doi: 10.1523/JNEUROSCI.3085-10.2010
Kitanishi T, Sakai J, Kojima S, Saitoh Y, Inokuchi K, Fukaya M, Watanabe M, Matsuki N, Yamada MK.
Activity-dependent localization in spines of the F-actin capping protein CapZ screened in a rat model of dementia.
Genes to Cells 15: 737-747 (2010)
doi: 10.1111/j.1365-2443.2010.01411.x
Kitanishi T, Ikegaya Y, Matsuki N, Yamada MK.
Experience-dependent, rapid structural changes in hippocampal pyramidal cell spines.
Cerebral Cortex 19: 2572-2578 (2009)
doi: 10.1093/cercor/bhp012
Tamura M, Tamura N, Ikeda T, Koyama R, Ikegaya Y, Matsuki N, Yamada MK.
Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers.
Molecular Brain 2: 2 (2009)
doi: 10.1186/1756-6606-2-2
Kahyo T, Ichikawa S, Hatanaka T, Yamada MK, Setou M.
A novel chalcone polyphenol inhibits the deacetylase activity of SIRT1 and cell growth in HEK293T cells.
Journal of Pharmacological Sciences 108: 364-371 (2008)
Sugiura Y, Shimma S, Konishi Y, Yamada MK, Setou M.
Imaging mass spectrometry technology and application on ganglioside study; visualization of age-dependent accumulation of C20-ganglioside molecular species in the mouse hippocampus.
PLOS ONE 3: e3232 (2008)
Yamada MK, Konishi Y, Kakinoki B, Ikegami K, Setou M.
Enhancement of Trk signaling pathways by the cholestane amide conjugate MCC-257.
Journal of Pharmacological Sciences 108: 131-134 (2008)
Chen J, Kitanishi T, Ikeda T, Matsuki N, Yamada MK.
Contextual learning induces an increase in the number of hippocampal CA1 neurons expressing high levels of BDNF.
Neurobiology of Learning and Memory 88: 409-415 (2007)
Koyama R, Muramatsu R, Sasaki T, Kimura R, Ueyama C, Tamura M, Tamura N, Ichikawa J, Takahashi N, Usami A, Yamada MK, Matsuki N, Ikegaya Y.
A low-cost method for brain slice cultures.
Journal of Pharmacological Sciences 104: 191-194 (2007)
Ikeda T, Tamura N, Matsuki N, Yamada MK.
Conserved role of brain-derived neurotrophic factor in Val66Met: target-selective reinforcement of GABAergic synapses.
Neuroreport 17: 1847-1851 (2006)
Ikeda T, Matsuki N, Yamada MK.
Estrogen produced in cultured hippocampal neurons is a functional regulator of a GABAergic machinery.
Journal of Nneuroscience Research 84: 1771-1777 (2006)
Tamura M, Koyama R, Ikegaya Y, Matsuki N, Yamada MK.
K252a, an inhibitor of Trk, disturbs pathfinding of hippocampal mossy fibers.
Neuroreport 17: 481-486 (2006)
Futatsugi A, Nakamura T, Yamada MK, Ebisui E, Nakamura K, Uchida K, Kitaguchi T, Takahashi-Iwanaga H, Noda T, Aruga J, Mikoshiba K.
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism.
Science 309: 2232-2234 (2005)
Ohba S, Ikeda T, Ikegaya Y, Nishiyama N, Matsuki N, Yamada MK.
BDNF locally potentiates GABAergic presynaptic machineries: target-selective circuit inhibition.
Cerebral Cortex 15: 291-298 (2005)
Kim JA, Koyama R, Yamada RX, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Environmental control of the survival and differentiation of dentate granule neurons.
Cerebral Cortex 14: 1358-1364 (2004)
Koyama R, Yamada MK, Fujisawa S, Katoh-Semba R, Matsuki N, Ikegaya Y.
Brain-derived neurotrophic factor induces hyperexcitable reentrant circuits in the dentate gyrus.
The Journal of Neuroscience 24: 7215-7224 (2004)
Koyama R, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Developmental switch in axon guidance modes of hippocampal mossy fibers in vitro.
Developmental Biology 267: 29-42 (2004)
Fujisawa S, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
BDNF boosts spike fidelity in chaotic neural oscillations.
Biophysical Journal 86: 1820-1828 (2004)
Baba A, Mitsumori K, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Beta-amyloid prevents excitotoxicity via recruitment of glial glutamate transporters.
Naunyn-Schmiedeberg’s Archives of Pharmacology 368: 234-238 (2003)
Baba A, Yasui T, Fujisawa S, Yamada RX, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Activity-evoked capacitative Ca2+ entry: implications in synaptic plasticity.
The Journal of Neuroscience 23: 7737-7741 (2003)
Nakao K, Ikegaya Y, Yamada MK, Nishiyama N, Matsuki N.
Fimbrial control of bidirectional synaptic plasticity of medial perforant path-dentate transmission.
Synapse 47: 163-168 (2003)
Tsukamoto M, Yasui T, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Mossy fibre synaptic NMDA receptors trigger non-Hebbian long-term potentiation at entorhino-CA3 synapses in the rat.
The Journal of Physiology 546: 665-675 (2003)
Kim JA, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Mossy fiber pathfinding in multilayer organotypic cultures of rat hippocampal slices.
Cellular and Molecular Neurobiology 23: 115-119 (2003)
Yamada MK, Nakanishi K, Ohba S, Nakamura T, Ikegaya Y, Nishiyama N, Matsuki N.
Brain-derived neurotrophic factor promotes the maturation of GABAergic mechanisms in cultured hippocampal neurons.
The Journal of Neuroscience 22: 7580-7585 (2002)
Nakao K, Ikegaya Y, Yamada MK, Nishiyama N, Matsuki N.
Hippocampal long-term depression as an index of spatial working memory.
The European Journal of Neuroscience 16: 970-974 (2002)
Ikegaya Y, Matsuura S, Ueno S, Baba A, Yamada MK, Nishiyama N, Matsuki N.
Beta-amyloid enhances glial glutamate uptake activity and attenuates synaptic efficacy.
The Journal of Biological Chemistry 277: 32180-32186 (2002)
Ueno S, Tsukamoto M, Hirano T, Kikuchi K, Yamada MK, Nishiyama N, Nagano T, Matsuki N, Ikegaya Y.
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits.
The Journal of Cell Biology 158: 215-220 (2002)
Kim JA, Mitsukawa K, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Cytoskeleton disruption causes apoptotic degeneration of dentate granule cells in hippocampal slice cultures.
Neuropharmacology 42: 1109-1118 (2002)
Ikegaya Y, Koyama R, Yamada MK, Nishiyama N, Matsuki N.
Rapid regrowth of hippocampal mossy fibres and preceding maturation of NMDA receptor-mediated neurotransmission.
The European journal of Neuroscience 15: 1859-1862 (2002)
Koyama R, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat.
The Journal of Physiology 539: 157-162 (2002)
Matsuura S, Ikegaya Y, Yamada MK, Nishiyama N, Matsuki N.
Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro.
GLIA 37: 178-182 (2002)
Baba A, Yamada MK, Nishiyama N, Matsuki N, Ikegaya Y.
Different Ca2+ dynamics between isolated hippocampal pyramidal cells and dentate granule cells.
Journal of Neurocytology 31: 41-48 (2002)
Muto Y, Nagao T, Yamada M, Mikoshiba K, Urushidani T.
A proposed mechanism for the potentiation of cAMP-mediated acid secretion by carbachol.
American Journal of Physiology. Cell Physiology 208: 155-165 (2001)
Michikawa T, Hirota J, Kawano S, Hiraoka M, Yamada M, Furuichi T, Mikoshiba K.
Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor.
Neuron 23:799-808 (1999)
Yoneshima H, Nagata E, Matsumoto M, Yamada M, Nakajima K, Miyata T, Ogawa M, Mikoshiba K.
A novel neurological mutant mouse, yotari, which exhibits reeler-like phenotype but expresses CR-50 antigen/reelin.
Neuroscience Research 29: 217-223 (1997)
Morikawa K, Ohbayashi T, Nakagawa M, Konishi Y, Makino Y, Yamada M, Miyawaki A, Furuichi T, Mikoshiba K, Tamura T.
Transcription initiation sites and promoter structure of the mouse type 2 inositol 1,4,5-trisphosphate receptor gene.
Gene 196:181-185 (1997)
Matsumoto M, Nakagawa T, Inoue T, Nagata E, Tanaka K, Takano H, Minowa O, Kuno J, Sakakibara S, Yamada M, Yoneshima H, Miyawaki A, Fukuuchi Y, Furuichi T, Okano H, Mikoshiba K, Noda T.
Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.
Nature 379: 168-171 (1996)
Yamada M, Miyawaki A, Saito K, Nakajima T, Yamamoto-Hino M, Ryo Y, Furuichi T, Mikoshiba K.
The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor.
The Biochemical Journal 308: 83-88 (1995)