出　版

［原著論文］

2006

［桐野　豊］

1.    Fukunaga, S., Matsuo, R., Hoshino, S., and Kirino, Y. (2006). A novel kruppel-like factor is induced by neuronal activity and by sensory input in the central nervous system of the terrestrial slug Limax valentianus. J Neurobiol 66,169-81.

2.    Kotani, S., Kawahara, S., and Kirino, Y. (2006). Purkinje cell activity during classical eyeblink conditioning in decerebrate guinea pigs. Brain Res 1068, 70-81.

3. Kishimoto, Y., Nakazawa, K., Tonegawa, S., Kirino, Y., and Kano, M. (2006). Hippocampal CA3 NMDA Receptors Are Crucial for Adaptive Timing of Trace Eyeblink Conditioned Response. J Neurosci 26, 1562-1570.

4. Takehara-Nishiuchi, K., Nakao, K., Kawahara, S., Matsuki, N., and Kirino, Y. (2006). Systems Consolidation Requires Postlearning Activation of NMDA Receptors in the Medial Prefrontal Cortex in Trace Eyeblink Conditioning. J Neurosci 26, 5049 – 5058.

5. Inoue, T., Murakami, M., Watanabe, S., Inokuma Y., and Kirino, Y. (2006). In Vitro Odor-Aversion Conditioning in a Terrestrial Mollusk,” J Neurophysiol 95, 3898-3903.

6. Ito, I., Watanabe, S., and Kirino, Y. (2006). Mapping of odor-related neuronal activity using a fluorescent derivative of glucose. Neurosci Lett 398, 224-229.

7. Shirahata, T., Tsunoda, M., Santa, T., Kirino, Y., and Watanabe, S. (2006). Depletion of serotonin selectively impairs short-term memory without affecting long-term memory in odor learning in the terrestrial slug Limax valentianus. Learn Mem 13, 267-270.

8. Kasai, Y., Watanabe, S., Kirino, Y., and Matsuo, R. (2006). The procerebrum is necessary for odor-aversion learning in the terrestrial slug Limax valentianus. Learn Mem 13, 482-488.

 [北村美一郎]

9. Homma, K., Kitamura, Y., Ogawa, H., and Oka, K. (2006). Serotonin induces the increase in intracellular Ca2+ which enhances neurite outgrowth in PC12 cells via the activation of 5-HT3 receptors and voltage-gated calcium channels. J Neurosci Res 84, 316-325.

[岸本泰司]

10. Kishimoto, Y., Nakazawa, S., Tonegawa, Y., Kirino, Y., and Kano, M. (2006). Hippocampal CA3 NMDA receptors are crucial for adaptive timing of trace eyeblink conditioned response. J Neurosci 26, 1562-1570.

11. Kishimoto, Y., and Kano, M. (2006). Endogenous cannabinoid signaling through the CB1 receptor is essential for cerebellum-dependent discrete motor learning. J Neurosci 26, 8829-8837.

 

2005

［桐野　豊］

1. Asaumi, M., Iijima, K., Sumioka, A., Ando-Iijima, K., Kirino, Y., Nakaya, T., and Suzuki, T. (2005). Interaction of N-terminal acetyltransferase with the cytoplasmic domain of b-amyloid precursor protein and its effect on Absecretion. J Biochem 137, 147-155.

2. Sakamoto, T., Takatsuki, K., Kawahara, S., Kirino, Y., Niki, H., Mishina, M. (2005). Role of hippocampal NMDA receptors in trace eyeblink conditioning. Brain Res 1039, 130-136.

3. Murakami, M., Kashiwadani, H., Kirino, Y., and Mori, K. (2005). State-Dependent Sensory Gating in Olfactory Cortex. Neuron 46, 285-296.

4. Kato, Y., Takatsuki, K., Kawahara, S., Fukunaga, S., Mori, H., Mishina, M., and Kirino, Y. (2005). NMDA receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunit δ2 mutant mice. Neuroscience 135, 1017-1023.

5. Takehara-Nisiuchi, K., Kawahara, S., and Kirino, Y. (2005). NMDA receptor-dependent processes in the medial prefrontal cortex are important for acquisition and early stage of consolidation during trace but not delay eyeblink conditioning. Learn Mem 12, 606-614.

6. Takatsuki, K., Kawahara, S., Mishina, M., and Kirino, Y. (2005). Characterization of hippocampal theta rhythm in wild-type mice and glutamate receptor subunit d2 mutant mice during eyeblink conditioning with a short trace interval. Brain Res 1063, 159-167.

[北村美一郎]

7. Kubota, T., Shindo, Y., Tokuno, K., Komatsu, H., Ogawa, H., Kudo, S., Kitamura, Y., Suzuki, K., and Oka, K. (2005). Mitochondria are intracellular magnesium stores: investigation by simultaneous fluorescent imagings in PC12 cells. Biochim Biophys Acta – Mol Cell Res 1744, 19-28.

8. Watanabe, H., Takaya, T., Ogawa, H., Kitamura, Y., and Oka, K. (2005). Influence of mRNA and protein synthesis inhibitors on the long-term memory acquisition of classically conditioned earthworms. Neurobiol Learn Mem 83, 151-157.

9. Komatsu, H., Miki, T., Citterio, D., Kubota, T., Shindoh, Y., Kitamura, Y., Oka, K., and Suzuki, K. (2005). Single molecular multianalyte (Ca2+, Mg2+) fluorescent probe and applications to bioimaging. J Am Chem Soc 127, 10798-10799.

 

2004

［桐野　豊］

1. Murakami, M., Watanabe, S., Inoue, T., and Kirino, Y. (2004) Odor-evoked responses in the olfactory center neurons in the terrestrial slug. J Neurobiol 58, 369–378.

2. Shirahata, T., Watanabe, S., and Kirino, Y. (2004). Distribution of serotonin-like immunoreactive neurons in the slug Limax valentianus. Cell Tissue Res 315, 285-290.

3. Inoue, T., Inokuma, Y., Watanabe, S., and Kirino, K. (2004). In Vitro Study of Odor-Evoked Behavior in a Terrestrial Mollusk. J Neurophysiol 91, 372-381.

4. Watanabe, S., Shimozono S., and Kirino, Y. (2004). Optical Recording of Oscillatory Neural Activities in the Molluscan Brain. Neurosci Lett 359, 147-150.

5. Ito, I., Kimura, T., Watanabe, S., Kirino Y., Ito, E. (2004). Modulation of Two Oscillatory Networks in the Peripheral Olfactory System by g-Aminobutyric Acid, Glutamate, and Acetylcholine in the Terrestrial Slug Limax marginatu. J Neurobiol 59, 304-318.

6. Takehara, T., Kwahara, S., Munemoto, Y., Kuriyama, H., Mori, H., Mishina, M., and Kirino, Y. (2004). The N-methyl-d-aspartate (NMDA)-type glutamate receptor GluRe2 is important for delay and trace eyeblink conditioning in mice. Neurosci Lett 364, 43-47.

7. Sakura, M., Kabetani, M., Watanabe, S., and Kirino, Y. (200). Impairment of olfactory discrimination by blockade of nitric oxide activity in the terrestrial slug Limax valentianus. Neurosci Lett 370, 257-261.

8. Yasui, K., Matsuo, R., and Kirino, Y. (2004). Onset of amnesia is delayed with a decrease in inhibition of protein synthesis during odor-taste associative learning in the terrestrial slug Limax valentianus. Zool Sci 21, 1163-1166.

[北村美一郎]

9. Mizutani, K., Shimoi, T., Kitamura, Y., Ogawa, H., Oka, K. (2004). Modulation of motor patterns by sensory feedback during earthworm locomotion. Neurosci Res 48, 457-462.

10. Komatsu, H., Iwasawa, N., Citterio, D., Suzuki, Y., Kubota, T., Tokuno, K., Kitamura, Y., Oka, K., and Suzuki, K. (2004). Design and synthesis of highly-sensitive and-selective fluorescein-derived magnesium fluorescent probes and application to intracellular 3D-Mg2+ imaging. J Am Chem Soc 126, 16353-16360.

11. Kubota, T., Shindo, Y., Tokuno, K., Komatsu, H., Ogawa, H., Kitamura, Y., Suzuki, K., and Oka, K. (2004). Investigation of intracellular magnesium mobilization pathways I PC12 cells B simultaneous Mg-Ca fluorescent imaging. J Am College of Nutrition 23, 742S-4S.

[窪田剛士]

12.   Yamaguchi, T., Kubota, T., Kanematsu, T., Nakayama, K., Hirata, M., and Yamamoto, T. (2004). Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1. Brain Res 1025, 237-240.

13.   Yamaguchi, T., Kubota, T., Watanabe, S., and Yamamoto, T. (2004). Activation of brain prostanoid EP3 receptors via arachidonic acid cascade during behavioral suppression induced by Delta8-tetrahydrocannabinol. J Neurochem 88, 148-154.

 

2003

［桐野　豊］

1. takatsuki, K., Kawahara, S., Kotani, S., Fukunaga, S., Mori, H., Mishina, M., and Kirino, Y. (2003). The hippocampus plays an important role in eyeblink conditioning with a short trace interval in glutamate receptor subunit d2 mutant mice. J Neurosci 23, 17-22.

2. Kotani, S., Kawahara S., and Kirino, Y. (2003). Trace eyeblink conditioning in decerebrate guinea pigs, Eur J Neurosci 17, 1445-1454.

3. Watanabe, S., Inoue, T., and Kirino, Y. (2003). Contribution of excitatory chloride conductance in the determination of the direction of traveling waves in an olfactory center. J Neurosci 23, 2932-2938.

4. Sumioka, A., Imoto, S., Martins, R. N., Kirino, Y., and Suzuki, T. (2003). XB51 isoforms mediate Alzheimer’s b-amyloid peptide production by X11L-dependent and -independent mechanisms. Biochem J 374, 261-268.

5. Takehara, K., Kawahara, S., and Kirino, Y. (2003). Time-dependent reorganization of the brain components underlying motor memory retention. J Neurosci 23, 9897-9905.

6. Ito, I., Watanabe, S., Kimura, T., Kirino, Y., and Ito, E. (2003). Negative Relationship between Odor-Induced Spike Activity and Spontaneous Oscillations in the Primary Olfactory System of the Terrestrial Slug Limax marginatus. Zool Sci 20, 1327-1335. [Zological Science Award受賞]

7. Ito, I., Watanabe, S., Kimura, T., Kirino, Y., and Ito, E. (2003). Distributions of Gamma-Aminobutyric Acid Immunoreactive and Acetylcholinesterase-Containing Cells in the Primary Olfactory System in the Terrestrial Slug Limax marginatus. Zool Sci 20, 1337-1346. [Zoological Science Award受賞]

8. Araki, Y., Tomita, S., Yamaguchi, H., Miyagi, N., Sumioka, A., Kirino, Y., and Suzuki, T. (2003). Novel Cadherin-related Membrane Proteins, Alcadeins, Enhance the X11-like Protein-mediated Stabilization of Amyloid-Protein Precursor Metabolism. J Biol Chem 278, 49448-49458.

9. Kotani, S., Kawahara, S., and Kirino, Y. (2003). Purkinje cell activities during learning a new timing in classical eyeblink conditioning. Brain Res 994, 193-202.

[北村美一郎]

10. Kubota, T., Tokuno, K., Nakagawa, K., Kitamura, Y., Ogawa, H., Suzuki, Y., Suzuki, K., and Oka, K. (2003). Na+/Mg2+ transporter acts as a Mg2+ buffering mechanism in PC12 cells”, Biochem Biophys Res Commun 303, 332-336.

11. Mizutani, K., Shimoi, T., Kitamura, Y., Ogawa, H., Oka, K. (2003). Identification of two types of synaptic activity in the earthworm nervous system during locomotion. Neuroscience 121, 473-478.

12. Kitamura, Y., Ogawa, H., and Oka, K. (2003). Real-time measurement of nitric oxide using a bio-imaging and an electrochemical technique. Talanta, 61, 717-724.

 

2002

［桐野　豊］

1. Takatsuki, K., Kawahara, S., Mori, H., Mishina M., and Kirino, Y. (2002). Scopolamine impairs eyeblink conditioning in the cerebellar LTD-deficient mice. NeuroReport 13, 159-162.

2. Kotani, S., Kawahara, S., and Kirino, Y. (2002). Classical eyeblink conditioning in the decerebrate guinea pigs. Eur J Neurosci 15, 1267-1270.

3. Inokuma, Y., Inoue, T., Watanabe, S., and Kirino, Y. (2002). Two Types of Network Oscillations and Their Odor Responses in the Primary Olfactory Center of a Terrestrial Mollusk. J Neurophysiol 87, 3160-3164.

4. Shimozono, S., Fukano, T., Nagai, T., Kirino, Y., Mizuno, H., and Miyawaki, A. (2002). Confocal imaging of subcellular Ca2+ concentrations using a dual-excitation ratiometric indicator based on green fluorescent protein. Sci.STKE (Signal Transduction Knowledge Environment) 2002/125/p14, 1-7.

5. Taru, H., Iijima, K., Hase, M., Kirino, Y., Yagi, Y., and Suzuki, T. (2002). Interaction of Alzheimer’s b-amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem 277, 20070-20078.

6. Taru, H., Kirino, Y., and Suzuki, T. (2002). Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism. J Biol Chem 277, 27567-27574.

7. Shibayama, S., Shibata-Seita, R., Miura, K., Kirino, Y., and Takishima, K. (2002). Identificqtion of a C-terminal region that is required for the nuclear translocation of ERK2 by passive diffusion. J Biol Chem 277, 37777-37782.

8. Takehara, K., Kawahara, S., Takatsuki, K., and Kirino, Y. (2002). Time-limited role of the hippocampus in the memory for trace eyeblink conditioning in mice. Brain Res 951, 183-190.

9. Takatsuki, K., Kawahara, S., Kotani, S., Mori, H., Mishina, M., and Kirino, Y. (2002). Hippocampal damage disrupts eyeblink conditioning in mice lacking glutamate receptor subunit d2. J Biol Phys 28, 539-547.

10. Matsuo, R., Hitomi, T., Watanabe, S., and Kirino, Y. (2002). Delayed-onset amnesia caused by protein synthesis inhibition in odor-taste associative memory of terrestrial slug Limax valentianus. Neurosci Lett 334, 201-205.

11. Kishimoto, Y., Fujimichi, R., Araishi, K., Kawahara, S., Kano, M., Aiba, A., and Kirino, Y. (2002). mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Eur J Neurosci 16, 2416-2424.

[北村美一郎]

12. Suzuki, Y., Komatsu, Y., Ikeda, T., Saito, N., Araki, S., Citterio, D., Hisamoto, H., Kitamura, Y., Kubota, T., Nakagawa, J., Oka, K., and Suzuki, K. (2002). Design and synthesis of Mg2+-selective fluoroionophores based on a coumarin derivative and application for the Mg2+ measurement in a living cell. Anal Chem 74, 1423-1428.

[岸本泰司]

14.   Kishimoto, Y., Fujimichi, R., Araishi, K., Kawahara, S., Kano, M., Aiba, A., and Kirino, Y. (2002). mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning. Eur J Neurosci 16, 2416-2424.

[窪田剛士]

15.   山口　拓, 野辺さより, 窪田剛志, 渡辺繁紀, 山本経之 (2002). 大麻成分テトラヒドロカンナビノールの異常行動における脳内プロスタグランジン合成経路の役割. 日本神経精神薬理学雑誌, 22: 209-210.

16.   山本経之, 山口　拓, 窪田剛志, 野辺さより, 渡邊繁紀 (2002). 精神分裂病、特にその陰性症状に脳内カンナビノイドが関与するか−動物実験からのアプローチ–. 精神薬療研究年報, 34: 179-184.

 

2001

［桐野　豊］

1. Nakaya, T., Kawahara, S., Watanabe, S., Suzuki, T., and Kirino, Y. (2001). Expression and Function of a Novel Gene in Odor-taste Associative Learning in the Terrestrial Slug. Genes Cells, 6, 43-56.

2. Kishimoto, Y., Kawahara, S., Mori, H., Mishina, M., and Kirino, Y. (2001). Long-trace Interval Eyeblink Conditioning Is Impaired in Mutant Mice Lacking NMDA Receptor Subunit e1. Eur J Neurosci 13, 1221-1227.

3. Kishimoto, Y., Kawahara, S., Suzuki, M., Mori, H., Mishina, M., and Kirino, Y. (2001). Classical Eyeblink Conditioning in Glutamate Receptor Subunit d2 Mutant Mice Is Impaired in Delay Paradigm But Not in Trace Paradigm. Eur J Neurosci 13, 1249-1253.

4. Watanabe, S., Inoue, T., Murakami, M., Inokuma, Y., Kawahara, S., and Kirino, Y. (2001). Modulation of Oscillatory Neural Activities by Cholinergic Activation of Interneurons in the Olfactory Center of a Terrestrial Slug. Brain Res 896, 30-35.

5. Shindo, K., Shinozaki, K., Kami, K., Anzai, K., Lee, S., Aoyagi, H., Kirino, Y., and Shimada, I. (2001). Solution Structure of Micelle-bound H5 Peptide (427-452): A Primary Structure Corresponding to the Pore-Forming Region of the Voltage Dependent Potassium Channel. Biochim Biophys Acta 1545, 153-159.

6. Satoh, Y., Hirakura, Y., Shibayama, S., Hirashima, N., Suzuki, T., Kirino. Y. (2001). b-Amyloid peptides inhibit acetylcholine release from cholinergic presynaptic nerve endings isolated from an electric ray. Neurosci Lett 302, 97-100.

7. Inoue, T., Watanabe, S., and Kirino, Y. (2001). Serotonin and NO Complementarily Regulate Generation of Oscillatory Activity in the Olfactory CNS of a Terrestrial Mollusk. J Neurophysiol 85, 2634-2638.

8. Takatsuki, K., Kawahara, S., Takehara, K., Kishimoto, Y., Kirino, Y. (2001). Effects of the noncompetitive NMDA receptor antagonist MK-801 on classical eyeblink conditioning in mice. Neurophamacol 41, 618-628.

9. Ando, K., Iijima, K., Elliott, J.I., Kirino, Y., and Suzuki, T. (2001). Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of b-amyloid. J Biol Chem 276, 40353-40361.

10. Kishimoto, Y., Hirono, M., Sugiyama, T., Kawahara, S., Nakao, K., Kishio, M., Katsuki, M., Yoshioka, T., and Kirino, Y. (2001). Impaired delay but normal trace eyeblink conditioning in PLCb4 mutant mice. Neuroreport 12, 2919-2922.

11. Kishimoto, Y., Suzuki, M., Kawahara, S., and Kirino, Y. (2001). Age-dependent impairment of delay and trace eyeblink conditioning in mice. Neuroreport 12, 3349-3352.

12. Kishimoto, Y., Kawahara, S., Fujimichi, R., Mori, H., Mishina, M., and Kirino, Y. (2001). Impairment of eyeblink conditioning in GluRd2 mutant mice depends on the temporal overlap between conditioned and unconditioned stimuli. Eur J Neurosci 14, 1515-1521.

13. Hirono, M., Sugiyama, T., Kishimoto, Y., Sakai, I., Miyazawa, T., Kishio, M., Inoue, H., Nakao, K., Ikeda, M., Kawahara, S., Kirino, Y., Katsuki, M., Horie, H., Ishikawa, Y., and Yoshioka, T. (2001). Phospholipase Cb4 and Protein Kinase Caand/or Protein Kinase CbI Are Involved in the Induction of Long-Term Depression in Cerebellar Purkinje Cells. J Biol Chem 276, 45236-45242.

14. Shimozono, S., Watanabe, S., Inoue, T., and Kirino, Y. (2001). Identification and characterization of an output neuron from the oscillatory molluscan olfactory network. Brain Res 921, 98-105.

15. Muto, Y., Matsuoka, T., Kida, A., Okano, Y., and Kirino, Y. (2001). Blepharismin, produced by the protozoan, Blepharisma japonicum, form ion-permeable channels in planar lipid bilayer membranes. FEBS Lett 508, 423-426.

［北村美一郎］

16. Kitamura, Y., Naganoma, Y., Horita, H., Tsuji, N., Shimizu, R., Ogawa, H., and Oka, K. (2001). Visualization of nitric oxide production in the earthworm ventral nerve cord. Neurosci Res 40, 175-181.

17. Kitamura, Y., Naganoma, Y., Horita, H., Ogawa, H., and Oka, K. (2001). Serotonin-induced nitric oxide production in the ventral nerve cord of the earthworm, Eisenia fetida. Neurosci Res 41, 129-134.

18. 北村美一郎，鵜澤智之，駒井豊，小川宏人，瀧澤直定，小林弘祐，谷下一夫，岡浩太郎 (2001). In vivo一酸化窒素（NO）測定のための同軸型微小電極. 生物物理，41: 32-34.

[岸本泰司]

19.   Takatsuki, K., Kawahara, S., Takehara, K., Kishimoto, Y., and Kirino, Y. (2001). Effects of the noncompetitive NMDA receptor antagonist MK-801 on classical eyeblink conditioning in mice. Neuropharmacol 41, 618-628.

20.   Hirono, M., Sugiyama, T., Kishimoto, Y., Sakai, I., Miyazawa, T., Kishio, M., Inoue, H., Nakao, K., Ikeda, M., Kawahara, S., Kirino, Y., Katsuki, M., Horie, H., Ishikawa, Y. & Yoshioka, T. (2001). Phospholipase Cb4 and protein kinase Ca and/or protein kinase CbI are involved in the induction of long term depression in cerebellar Purkinje cells. J Biol Chem 276, 45236-45242.

21.   Kishimoto, Y., Kawahara, S., Mori, H., Mishina, M., and Kirino, Y. (2001). Long-trace interval eyeblink conditioning is impaired in mutant mice lacking the NMDA receptor subunit e1. Eur J Neurosci 13, 1221-1227.

22.   Kishimoto, Y., Suzuki, M., Kawahara, S., and Kirino, Y. (2001). Age-dependent impairment of delay and trace eyeblink conditioning in mice. NeuroReport 12, 3349-3352.

23.   Kishimoto, Y., Hirono, M., Sugiyama, T., Kawahara, S., Nakao, K., Kishio, M., Katsuki, M., Yoshioka, T., and Kirino, Y. (2001). Impaired delay but normal trace eyeblink conditioning in PLCb4 mutant mice. NeuroReport 12, 2919-2922.

24.   Kishimoto, Y., Kawahara, S., Suzuki, M., Mori, H., Mishina, M., and Kirino, Y. (2001). Classical eyeblink conditioning in glutamate receptor subunit d2 mutant mice is impaired in the delay paradigm but not in the trace paradigm. Eur J Neurosci 13, 1249-1253.

25.   Kishimoto, Y., Kawahara, S., Fujimichi, R., Mori, H., Mishina, M., and Kirino, Y. (2001). Impairment of eyeblink conditioning in GluRd2 mutant mice depends on the temporal overlap between conditioned and unconditioned stimuli. Eur J Neurosci 14, 1515-1521.