Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University

Publication

[Original papers]

2014

1. Yoshihisa Kato, Koichi Haraguchi, Mao Onishi, Shinichi Ikushiro, Tetsuya Endo, Chiho Ohta, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa: 3,3',4,4'-Tetrachlorobiphenyl-Mediated Decrease of Serum Thyroxine Level in C57BL/6 and DBA/2 Mice Occurs Mainly through Enhanced Accumulation of Thyroxine in the Liver. Biol. Pharm. Bull., (2014) 37, 504-509.
2. Yukiko Fujii, Eri Nishimura, Yoshihisa Kato, Kouji H. Harada, Akio Koizumi, and Koichi Haraguchi: Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan. Environ. Int., (2014) 63, 19-25.
3. Futoshi Matsubara, Yasuko Sagara, Yoshihisa Kato, Kouji Harada, Akio Koizumi, and Koichi Haraguchi: Detection of Antibodies to Human T-Cell Leukemia Virus Types 1 and 2 in Breast Milk from East Asian Women. Biol. Pharm. Bull., (2014) 37, 311-314.
4. Osamu Kimura, Chiho Ohta, Nobuyuki Koga, Koichi Haraguchi, Yoshihisa Kato, and Tetsuya Endo: Carrier-mediated uptake of Nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells. Food Chemistry, (2014) 154, 145-150.

2013

1. Yoshihisa Kato, Mao Onishi, Koichi Haraguchi, Shinichi Ikushiro, Chiho Ohta, Nobuyuki Koga, Tetsuya Endo, Shizuo Yamada, and Masakuni Degawa: A possible mechanism for 2,3',4,4',5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level in mice. Biol. Pharm. Bull., (2013) 36, 1594-1601. (Highlighted paper selected by Editor-in-Chief)
2. Noriaki Hidaka, Katsuya Suemaru, Yoshihisa Kato, and Hiroaki Araki: Involvement of α4β2 nicotinic acetylcholine receptors in working memory impairment induced by repeated electroconvulsive seizures in rats. Epilepsy Research, (2013) 104, 181-185.
3. Tetsuya Endo, Yohsuke Hisamichi, Osamu Kimura, Hideki Ogasawara, Chiho Ohta, Nobuyuki Koga, Yoshihisa Kato, and Koichi Haraguchi: Levels of Mercury in Muscle and Liver of Star-Spotted Dogfish (Mustelus manazo) from the Northern Region of Japan: A Comparison with Spiny Dogfish (Squalus acanthias). Arch. Environ. Contam. Toxicol., (2013) 64, 467-474.
4. Norikazu Sakakibara, Takayuki Hamasaki, Masanori Baba, Yosuke Demizu, Masaaki Kurihara, Kohji Irie, Masatoshi Iwai, Eriko Asada, Yoshihisa Kato, and Tokumi Maruyama: Synthesis and evaluation of novel 3-(3,5-dimethylbenzyl)uracil analogs as potential anti-HIV-1 agents. Bioorg. Med. Chem., (2013) 21, 5900-5906.
5. Norikazu Sakakibara, Ikuko Tsukamoto, Yohei Isono, Maki Takata, Ryoji Konishi, Yoshihisa Kato, and Tokumi Maruyama: A new method for synthesis and angiogenic evaluation of leteprinim potassium and its novel analogs. Heterocycles, (2013) 87, 2369-2384.
6. Toshiaki Umezawa, Safendrri Komara Ragamustari, Tomoyuki Nakatsubo, Shohei Wada, Laigeng Li, Masaomi Yamamura, Norikazu Sakakibara, Takefumi Hattori, Shiro Suzuki, and Vincent L. Chiang: A lignan O-methyltransferase catalyzing the regioselective methylation of matairesinol in Carthamus tinctorius. Plant Biotechnology, (2013) 30, 97-109.
7. Naohiko Okabe, Emi Nakamura, Naoyuki Himi, Kazuhiko Narita, Ikuko Tsukamoto, Tokumi Maruyama, Norikazu Sakakibara, Takehiro Nakamura, Toshifumi Itano, and Osamu Miyamoto: Delayed administration of the nucleic acid analog 2Cl-C.OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke. Brain Research, (2013) 1506, 115-131.
8. 太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸： 2,2',3,4',5,5'-六塩素化ビフェニル（CB146）のin vitro代謝の動物種差．福岡医学雑誌、(2013) 104, 161-169.
9. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Osamu Kimura, Nobuyuki Koga : In vitro metabolism of 2,2',4,4',5-pentachlorobiphenyl (CB99) by rat and guinea pig liver microsomes. Organohalogen Compounds, (2013) 75, 587-590.
10. 榊原紀和、丸山徳見、加藤善久: 血管新生促進作用および抗HIV-1作用を有する新規核酸類縁体の創製. 香川県薬剤師会会誌 かがやく、(2013) 150, 68-70.
11. 太田千穂、加藤善久、原口浩一、遠藤哲也、古賀信幸： ラットおよびモルモットの小腸と腎におけるノビレチンの代謝: 中村学園大学・中村学園大学短期大学部研究紀要、(2013) 45, 141-149.

[原著論文等]

2012

1. Yoshihisa Kato, Sekihiro Tamaki, Koichi Haraguchi, Shin-ichi Ikushiro, Masashi Sekimoto, Chiho Ohta, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa: Comparative study on 2,2',4,5,5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level between C57BL/6 and its transthyretin-deficient mice. Toxicol. Appl. Pharmacol., 263, 323-329 (2012).
2. Yoshihisa Kato, Syohei Okada, Kazutaka Atobe, Tetsuya Endo, and Koichi Haraguchi: Selective determination of mono- and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass spectrometry. Anal. Bioanal. Chem., 404, 197-206 (2012).
3. Norikazu Sakakibara, Ikuko Tsukamoto, Takashi Tsurura, Maki Takata, Ryoji Konishi, and Tokumi Maruyama: Novel synthesis of carbocyclic oxetanocin analogs (2-Alkoxy-C.OXT-A) and their tube formation activities of human umbilical vein endothelial cells (HUVEC). Heterocycles, 85, 1105-1116（2012）.
4. Paula Ordonez, Takayuki Hamasaki, Yohei Isono, Norikazu Sakakibara, Masahiro Ikejiri, Tokumi Maruyama, and Masanori Baba: Anti-human immunodeficiency virus type 1 activity of novel 6-substituted 1-benzyl-3-(3,5-dimethylbenzyl)uracil derivatives. Antimicrob. Agents Chemother., 56, 2581-2589 (2012)
5. Norikazu Sakakibara, Ai Kakoh, and Tokumi Maruyama: First synthesis of [6-¹⁵N]-cladribine using ribonucleoside as a starting material. Heterocycles, 85, 171-182 (2012)
6. Yoshihisa Kato, Sekihiro Tamaki, Koichi Haraguchi, Shin-ichi Ikushiro, Masashi Sekimoto, Chiho Ohta, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa : 2,2',4,5,5'-Pentachlorobiphenyl-mediated inhibition of a serum T₄-transthyretin complex formation is one of causes for the PCB-induced changes in the serum and hepatic T₄ levels in mice. Organohalogen Compounds, 74, 1377-1380 (2012)
7. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga: Involvement of rat CYP3A enzymes in the metabolism of 2,2',3,4',5',6-hexachlorobiphenyl (CB149). Organohalogen Compounds, 74, 1475-1478 (2012)
8. 太田千穂、原口浩一、遠藤哲也、加藤善久、松原　大、古賀信幸： 海洋生物由来の2,4,6-tribromoanisoleの動物肝ミクロゾームによる代謝とその関連化合物の抗酸化活性: 中村学園大学・中村学園大学短期大学部研究紀要、44, 215-224 (2012)

2011

1. Yoshihisa Kato, Mao Onishi, Koichi Haraguchi, Shinichi Ikushiro, Chiho Ohta, Nobuyuki Koga, Tetsuya Endo, Shizuo Yamada, and Masakuni Degawa: A possible mechanism for 2,2',4,4',5,5'-hexachlorobiphenyl-mediated decrease in serum thyroxine level in mice. Toxicol. Appl. Pharmacol., 254, 48-55 (2011)
2. Misaka Shingen, Kurosawa Souhei, Shinya Uchida, Yoshida Akira, Yoshihisa Kato, Yoshiyuki Kagawa, Shizuo Yamada: Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy. J Pharm Pharmacol., 63, 58-64 (2011)
3. Nobuyuki Koga, Chiho Ohta, Yoshihisa Kato, Koichi Haraguchi, Tetsuya Endo, Kazunori Ogawa, Hideaki Ohta, and Masamichi Yano: In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450. Xenobiotica, 41, 927-933 (2011)
4. Koichi Haraguchi, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga, and Tetsuya Endo: Marine sponge: A potential source for methoxylated polybrominated diphenyl ethers in the Asia-Pacific food web. J. Agric. Food Chem., 59、13102-13109 (2011)
5. 太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸： 2,2',3,4,4',5'-六塩素化ビフェニル（CB138）のモルモットにおけるin vivo代謝．福岡医学雑誌、102、167-174(2011)
6. 太田千穂、枩岡樹子、加藤善久、原口浩一、遠藤哲也、古賀信幸： フェニルプロパノイド類とフラボノイド類の抗酸化作用とα-グルコシダーゼ阻害作用：構造活性相関: 中村学園大学・中村学園大学短期大学部研究紀要、43、243-249(2011)

2010

1. Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa: A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice. Drug Metab. Dispos., 38, 150-156 (2010)
2. Yoshihisa Kato, Koichi Haraguchi, Yuriko Ito, Aki Fujii, Tomoaki Yamazaki, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa: Polychlorinated biphenyl-mediated decrease in serum thyroxine level in rodents. Drug Metab. Dispos., 38, 697-704 (2010)
3. Yoshihisa Kato, Hiroshi Suzuki, Koichi Haraguchi, Shinichi Ikushiro, Yoshihiko Ito, Shinya Uchida, Shizuo Yamada and Masakuni Degawa: A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents. Toxicol. Appl. Pharmacol., 249, 238-246 (2010)
4. Yoshihiko Ito, Taketsugu Harada, Kasumi Fushimi, Yoshiyuki Kagawa, Hidenobu Oka, Hiroshi Nakazawa, Reiko Homma, Yoshihisa Kato and Shizuo Yamada: Pharmacokinetic and pharmacodynamic analysis of acetylcholinesterase inhibition by distigmine bromide in rats. Drug Metab. Pharmacokinet., 25, 254-261 (2010)
5. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Futoshi Matsubara and Nobuyuki Koga : Species difference in the in vitro metabolism of 2,2',3,4,4',5,5'-heptachlorobiphenyl (CB180). Organohalogen Compounds 72, 1796-1799 (2010)
6. 太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸: 2,3',4,5,5'-Pentachlorobiphenyl (CB120)とその予想代謝物の合成 中村学園大学・中村学園大学短期大学部研究紀要、42、333-338 (2010)

2009

1. Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa: 4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver. Drug Metab. Dispos., 37, 2095-2102 (2009)
2. Yoshihisa Kato, Syohei Okada, Kazutaka Atobe, Tetsuya Endo, Futoshi Matsubara, Takayoshi Oguma and Koichi Haraguchi: Simultaneous determination by APCI-LC/MS/MS of hydroxylated and methoxylated polybrominated diphenyl ethers found in marine biota. Anal. Chem., 81, 5942-5948 (2009)
3. Tetsuya Endo, Yohsuke Hisamichi, Osamu Kimura, Yuichi Kotaki, Yoshihisa Kato, Chiho Ohta, Nobuyuki Koga and Koichi Haraguchi: Contamination levels of mercury in the muscle of female and male spiny dogfishes (Squalus acanthias) caught off the coast of Japan. Chemosphere, 77, 1333-1337 (2009)
4. Takashi Okura, Tadahiro Ozawa, Michiko Ibe, Yuko Taki, Midori Kimura, Yoshiyuki Kagawa, Yoshihisa Kato and Shizuo Yamada: Effects of repeated morphine treatment on the antinociceptive effects, intestinal absorption, and efflux from intestinal epithelial cells of morphine. Biol. Pharm. Bull., 32, 1571-1575 (2009)
5. Koichi Haraguchi, Akio Koizumi, Kayoko Inoue, Kouji H. Harada, Toshiaki Hitomi, Mutsuko Minata, Miyako Tanabe, Yoshihisa Kato, Eri Nishimura, Yoshiaki Yamamoto, Takao Watanabe, Katsunobu Takenaka, Shigeki Uehara, Hye-Ran Yang, Min-Young Kim, Chan-Seok Moon, Hae-Sook Kim, Peiyu Wang, Aiping Liu and Nguyen Ngoc Hung: Levels and regional trends of persistent organochlorines and polybrominated diphenyl ethers in Asian breast milk demonstrate POPs signatures unique to individual countries. Environ. Int., 35, 1072-1079 (2009)
6. Koichi Haraguchi, Yohsuke Hisamichi, Yuichi Kotaki, Yoshihisa Kato and Tetsuya Endo: Halogenated bipyrroles and methoxylated tetrabromodiphenyl ethers in tiger shark (Galeocerdo cuvier) from the southern coast of Japan. Environ. Sci. Technol., 43, 2288-2294 (2009)
7. 太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸： 2,2',5,5'-四塩素化ビフェニル(CB52)のウサギ肝ミクロゾームによる代謝. 福岡医学雑誌、100、200-209 (2009)
8. Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa : A possible mechanism for the decrease in serum thyroxine level by TCDD-like PCB, 3,3',4,4',5-pentachlorobiphenyl in mice. Organohalogen Compd., 71, 119-122 (2009)
9. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo and Nobuyuki Koga : Metabolism of 2,2',3,4',5',6-hexachlorobiphenyl (CB149) by liver microsomes from rats, hamsters, guinea pigs and humans. Organohalogen Compd., 71, 308-311 (2009)
10. 太田千穂、枩岡樹子、太田英明、加藤善久、古賀信幸: 植物成分diosmetinおよびhesperetinのラット肝ミクロゾームによるin vitro代謝 中村学園大学・中村学園大学短期大学部研究紀要、41、247-254 (2009)

2008

1. Yoshihisa Kato, Shin-ichi Ikushiro, Yoshikazu Emi, Sekihiro Tamaki, Hiroshi Suzuki, Toshiyuki Sakaki, Shizuo Yamada and Masakuni Degawa: Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine T4 in humans. Drug Metab. Dispos., 36, 51-55 (2008)
2. Koichi Haraguchi, Yoshihisa Kato, Kazutaka Atobe, Syohei Okada, Tetsuya Endo, Futoshi Matsubara and Takayoshi Oguma: Negative APCI-LC/MS/MS method for determination of natural persistent halogenated products in marine biota. Anal. Chem., 80, 9748-9755 (2008)
3. Tetsuya Endo, Yohsuke Hisamichi, Koichi Haraguchi, Yoshihisa Kato, Chiho Ohta and Nobuyuki Koga: Hg, Zn and Cu levels in the muscle and liver of tiger sharks (Galeocerdo cuvier) from the coast of Ishigaki Island, Japan: Relationship between metal concentrations and body length. Mar. Pollut. Bull., 56, 1774-1780 (2008)
4. Aiko Kageyama, Tomomi Fujino, Yuko Taki, Yoshihisa Kato, Yoshihisa Nozawa, Yoshihiko Ito and Shizuo Yamada: Alteration of muscarinic and purinergic receptors in urinary bladder of rats with cyclophosphamide-induced interstitial cystitis. Neuroscience Letters, 436, 81-84 (2008)
5. Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa: A possible mechanism for the decrease in serum thyroxine level by 4-OH-2,2',3,4',5,5',6-heptachlorobiphenyl in mice. Organohalogen Compd., 70, 1601-1604 (2008)
6. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Mikiko Matsuoka and Nobuyuki Koga : Metabolism of 2,2',3,4',5,5'-hexachlorobiphenyl (CB146) by liver microsomes from rats, hamsters and guinea pigs. Organohalogen Compd., 70, 1185-1188 (2008)

2007

1. Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa: A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine level in rats. Drug Metab. Dispos., 35, 1949-1955 (2007)
2. Yoshikazu Emi, Shin-ichi Ikushiro and Yoshihisa Kato: Thyroxine-metabolizing rat UDP-glucuronosyltransferase 1A7 is regulated by thyroid hormone receptor. Endocrinology, 148, 6124-6133 (2007)
3. Nobuyuki Koga, Miki Matsuo, Chiho Ohta, Koichi Haraguchi, Mikiko Matsuoka, Yoshihisa Kato, Toshinao Ishii, Masamichi Yano and Hideaki Ohta: Comparative study on nobiletin metabolism with liver microsomes from rats, guinea pigs and hamsters and rat cytochrome P450. Biol. Pharm. Bull., 30, 2317-2323 (2007)
4. Shinya Uchida, Souhei Kurosawa, Tomomi Fujino (Oki), Yoshihisa Kato, Masato Nanri, Kenichiro Yoshida and Shizuo Yamada: Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain. Life Sci., 80, 2454-2460 (2007)
5. 太田千穂、枩岡樹子、原口浩一、加藤善久、遠藤哲也、古賀信幸: 2,2',4,5,5'-五塩素化ビフェニル(CB101)のラット、ハムスターおよびモルモット肝ミクロゾームによる代謝. 福岡医学雑誌、98、236-244 (2007)
6. Nobuyuki Koga, Chiho Ohta, Koichi Haraguchi, Mikiko Matsuoka, Yoshihisa Kato and Tetsuya Endo: The formation of a catechol metabolite of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes from rats, hamsters, guinea pigs and humans. Organohalogen Compd., 69, 1757-1760 (2007)
7. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Mikiko Matsuoka, Tetsuya Endo and Nobuyuki Koga : The distribution of metabolites of 2,2',3,4,4',5',6-heptachlorobiphenyl (CB183) in rats and guinea pigs. Organohalogen Compd., 69, 1761-1764 (2007)
8. Kazutaka Atobe, Tatsuhiro Ishida, Emi Ishida, Kouichi Hashimoto, Hideo Kobayashi, Jyunko Yasuda, Takanori Aoki, Ken-ichi Obata, Hiroshi Kikuchi, Hidetaka Akita, Tomohiro Asai, Hideyoshi Harashima, Naoto Oku and Hiroshi Kiwada : In vitro efficacy of a sterically stabilized immunoliposomes targeted to membrane type 1 matrix metalloproteinase (MT1-MMP). Biol. Pharm. Bull., 30, 972-978 (2007)
9. Lap Thi Nguyen, Kazutaka Atobe, Jose Mario Barichello, Tatsuhiro Ishida and Hiroshi Kiwada : Complex formation with plasmid DNA increases the cytotoxicity of cationic liposomes. Biol. Pharm. Bull., 30, 751-757 (2007)
10. 跡部一孝：癌および新生血管を標的としたMT1-MMPターゲットリポソームに関する研究. Progress in Drug delivery system, 16, 27-32 (2007)

2006

1. Shin-ichi Ikushiro, Yoshikazu Emi, Yoshihisha Kato, Shizuo Yamada and Toshiyuki Sakaki: Monospecific antipeptide antibodies against human hepatic UDP-glucuronosyltransferase 1A subfamily (UGT1A) isozymes. Drug Metab. Pharmacokinet., 21, 70-74 (2006)
2. Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Sekihiro Tamaki, Koichi Haraguchi, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa : A possible mechanism for the decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats. Organohalogen Compd., 68, 1442-1445 (2006)
3. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Ozaki Mari and Nobuyuki Koga : In vitro metabolism of 2,2',3,4,4',5',6-heptachlorobiphenyl (CB183) with liver microsomes from rats, guinea pigs and hamsters. Organohalogen Compd., 68, 1733-1736 (2006)
4. Tatsuhiro Ishida, Kazutaka Atobe, XingYu Wang and Hiroshi Kiwada : Accelerated blood clearance of PEGylated liposomes upon repeated injections: Effect of doxorubicin-encapsulation and high-dose first injection. J. Control. Release, 115, 251-258 (2006)

2005

1. Ayako Ohnishi, Yoshitaka Yano, Toru Ishibashi, Takayuki Katsube and Takayoshi Oguma : Evaluation of bayesian predictability of Vancomycin concentration using population pharmacokinetic parameters in pediatric patients. Drug Metab. Pharmacokinet., 26, 415-422 (2005)
2. Yoshihisa Kato, Hiroshi Suzuki, Shinichi Ikushiro, Shizuo Yamada and Masakuni Degawa: Decrease in serum thyroxine level by phenobarbital in rats is not necessarily dependent on increase in hepatic UDP-glucuronosyltransferase. Drug Metab. Dispos., 33, 1608-1612 (2005)
3. Yoshihisa Kato, Koichi Haraguchi, Tomoaki Yamazaki, Ryohei Kimura, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa: The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice: No correlation with formation of methylsulfonyl metabolites. Drug Metab. Dispos., 33, 1661-1665 (2005)
4. Koichi Haraguchi, Yoshihisa Kato, Nobuyuki Koga and Masakuni Degawa: Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs. Xenobiotica, 35, 85-96 (2005)
5. Koichi Haraguchi, Nobuyuki Koga and Yoshihisa Kato: Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters, and guinea pigs. Drug Metab. Dispos., 33, 373-380 (2005)
6. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato and Nobuyuki Koga: In vitro metabolism of 2,2',3,4',5,5',6-heptachlorobiphenyl (CB187) by liver microsomes from rats, hamsters and guinea pigs. Xenobiotica, 35, 319-330 (2005)
7. 太田千穂、原口浩一、加藤善久、古賀信幸：2,3',4,4',5-五塩素化ビフェニル（CB118）のモルモット肝ミクロゾームによる代謝．福岡医学雑誌、96、232-240 (2005)
8. Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato and Nobuyuki Koga: In vivo metabolism of 2,2',3,4',5,5',6-heptachlorobiphenyl (CB187) in guinea pigs. Organohalogen Compd., 67, 2343-2345 (2005)

2004

1. Toshihiro Wajima, Yoshitaka Yano, Kazuya Fukumura and Takayoshi Oguma Prediction of human pharmacokinetic profile in animal scale up based on normalizing time course profiles. J. Pharm. Sci., 93, 1890-1900 (2004)
2. Yoshihisa Kato, Shinichi Ikushiro, Koichi Haraguchi, Tomoaki Yamazaki, Yuriko Ito, Hiroshi Suzuki, Ryohei Kimura, Shizuo Yamada, Tohru Inoue and Masakuni Degawa: A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats. Toxicol. Sci., 81, 309-315 (2004)
3. Kelly J. Gauger, Yoshihisa Kato, Koichi Haraguchi, Hans-Joachim Lehmler, Larry W. Robertson, Ruby Bansal and R. Thomas Zoeller: Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors. Environ. Health Perspect., 112, 516-523 (2004)
4. Koichi Haraguchi, Yoshihisa Kato, Nobuyuki Koga and Masakuni Degawa: Metabolism of polychlorinated biphenyls by Gunn rats: Identification and serum retention of catechol metabolites. Chem. Res. Toxicol., 17, 1684-1691 (2004)
5. Nobuyuki Koga, Chiho Ohta, Koichi Haraguchi, Tomoyo Kanamaru, Yoshihisa Kato and Shizuo Yamada: In vitro metabolism of 2,2',3,4',5,5',6-heptachlorobiphenyl (CB187) with liver microsomes of rats, hamsters and guinea pigs. Organohalogen Compd., 66, 2882-2886 (2004)

[総説・著書]

1. 加藤善久: 薬物の体内動態と薬効・毒性発現メカニズムの解明を目指して．薬剤学、70、303-308 (2010)
2. Nobuyuki Koga, Chiho Ohta, Koichi Haraguchi, Mikiko Matsuoka, Yoshihisa Kato and Tetsuya Endo: The formation of a catechol metabolite of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes from rats, hamsters, guinea pigs and humans. Persistent Organic Pollutants (POPs) Research in Asia, Edited by Masatoshi Morita, pp.292-297, DIOXIN2007 International symposium organizing committee (2008)
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